lun

Research on Formation Forms and Evolution of Shandong Prehistoric Population Based on GIS

Based on the analysis of the accumulation characteristics and spatio-temporal distribution charac-teristics of Neolithic settlement sites in Shandong Province, this paper discusses the inheritance mode of settlements in Shandong Province and the relationship between spatio-temporal distribu-tion and environmental evolution. The results show that the accumulation form of Neolithic sites in Shandong is mainly a single type (accounting for 80.69%), and the cultural inheritance model is continuous and relatively stable in the central and southern part of Shandong, while intermittent and unstable in the northwest of Shandong. The number of sites shows a law of increase-sharp in-crease-decrease. The spatial distribution of sites is also regular. The distribution of post-Li cultural sites is centralized and mostly distributed according to water, the distribution of sites in the period of Beixin culture extends to the east and west, and the distribution of sites in the period of Dawen-kou culture extends to the south. It covers the whole region in the period of Longshan culture, but it shrinks significantly in the period of Yueshi culture, especially in the low-altitude plain area. The warm and humid climate 8000~5000 years ago promoted the sustainable development of the early and middle Neolithic culture, while the warm climate decreased but still suitable for 5000~4000 years ago, the coastline retreated continuously, and Longshan culture flourished and developed. However, the cooling, frequent flood disasters and wars around 4000 years ago led to the significant decline of Longshan culture, which was replaced by Yueshi culture.

Continue Reading

Frozen electron microscope single particle image recognition based on bilateral filtering and limited Bolzman machine

Cryo-EM is a crucial technological means to study protein and nucleic acid of structural biology which is originated in 1970s. The significant evolution of computing performance and direct electronic detection (DDD) camera make the atomic resolution of 3D structure of micromolecular under the condition of small dose possible since 21st century. The reconstruction of 3D model is based on identification and classification of 2D Cryo-EM single particle projection images which becomes an immediate cause of how good the resolution of final 3D model could share. Currently, the 2D single particle images selection was is such a time-consuming job even for the experienced scientific researchers as the signal noise ratio (SNR) is usually quite low. A new approach with the combination of computer graphics and machine learning is raised to this problem by using bilateral filter to optimize the detail of edge and histogram equalization to enhance graphic information in the pre-processing stage, moreover, small amount of high-confidence images was chosen as training sample under the restricted Boltzmann machine (RBM) network in supervised learning pattern to achieve the image selection and classification. In the verification stage, the effectiveness of this approach is proved to work well with simulated low SNR projection photos generated from the known micromolecular data from protein data bank (PDB). Subsequently, actual experimental 2D singlet particle data of transient receptor potential cation channel subfamily V member 1 (TRPV1) is applied to be identified and classified, and finally, a 3.6Å 3D structural model is reconstructed through cryoSPARC platform by using only approximate 53% of the original data. Consequently, this research is not only improving the manual efficiency, but also providing a broader perspective the identification of Cryo-EM single particle 2D images.

Continue Reading

Optimization of urban settlement monitoring scheme based on hierarchical analysis

Subsidence monitoring can effectively reflect the changes of ground elevation in time and provide important technical support and decision-making suggestions for the rapid development of cities. However, the selection of urban subsidence monitoring is often affected by factors such as budget, region, etc., the traditional method is arbitrary and subjective, and difficult to balance the observa-tion accuracy and economic cost. To solve the above problems, this paper proposes an optimal se-lection method of urban subsidence monitoring based on AHP. Through the construction of judg-ment matrix, consistency test and weight calculation of influence factors, the qualitative and quan-titative decision analysis method is used to comprehensively evaluate the land subsidence observa-tion scheme in a specific city. The experimental results show that the scheme of using GPS to moni-tor the land subsidence in this city is better than the traditional leveling. The GPS observation can meet the accuracy and effectively save manpower, time and economic costs. The relevant results can provide reference for the selection of other surveying and mapping projects.

Continue Reading

Separation study of pleat bacteria

Entoloma (Fr.) P. Kumm. is a large and complex classification group, so it is necessary to conduct in-depth and systematic research. In this paper, the research progress of Etoloma is reviewed, which is the theoretical basis for the study of Entoloma.

Continue Reading

Prediction of ARIMA Model Based on Season Effects on New Employment Number of Towns in Guizhou Province

“Poverty alleviation” is a long-term battle, and the key tasks of poverty alleviation have been steadily advanced. Among them, Guizhou Province, which has more impoverished counties, has achieved remarkable results in poverty alleviation. This paper selects monthly data of the number of urban employment growth in Guizhou Province from 2002 to 2019 for time series analysis, establishes a seasonal product ARIMA model, and uses the built model to predict the number of urban employment growth in Guizhou Province in 2020, conducting a robustness test to illustrate reliability of predictions. The forecast results indicate that the newly-increased urban employment population in 2020 will still maintain seasonality and growth.

Continue Reading

Statistical Inference of Stratified Linear Regression Model Based on Nested Structure

Generally, when dealing with the problem of model hypothesis testing, statistical inference is the main method to infer the population through the observation information of sample data. In this paper, the coefficient vector diagnosis method of Hierarchical Linear Regression Model based on nested structure is proposed. For the first level model coefficient diagnosis of hierarchical linear regression, the traditional F-test of linear nested regression model is used for statistical inference. The innovation of this paper lies in the statistical diagnosis of the second layer coefficient of Hierarchical Linear Regression Model. The nested multiple linear regression model is extended to the Hierarchical Linear Regression Model with nested structure. The likelihood function ratio of Hierarchical Linear Regression Model is mainly constructed to construct the test statistics. The effectiveness and feasibility of this method is verified by the hierarchical data analysis of college mathematics scores.

Continue Reading

Climate Adaptive City Plan Based on Ecological Civilization Idea

Climate conditions and urban planning and construction have always been symbiotic system. The ancients in our country followed the natural view of the harmony between man and nature when built cities, they integrated local climate conditions effectively to create a good living environment. However, the relationship between climate and urban construction is ignored gradually with the development of science and technology in modern society. The disordered urban sprawl has caused many climate problems, such as urban heat island, dry island, rain island, and weak winds, which have an impact on urban livability, human comfort and health. Therefore, the “Urban Climate As-sessment Team” advocates and publicizes the concept of urban planning that should take climatic adaptability and ecological environment as guide. The purpose is to improve the urban resiliency and the ability to adapt to climate change, create an ecological and livable urban environment. The team has formed a scientific and quantitative assessment system of climate effects, including urban heat island effects, urban ventilation corridors and rainstorms, which has promoted innovation of technology effectively and has been applied in many urban planning in China. The team has created a new point for urban planning that is adapted to the ecological civilization construction and has guaranteed ecological and sustainable city effectively.

Continue Reading

Analysis of risk factors of impermaneous symptoms of implantation of implantated cardiac electronic devices, predictive value of prognosis and inflammatory factors

Objective: To investigate the risk factors, prognosis and the predictive value of 5 different inflammatory factors in CIED associated subclinical generator pocket infections (asymptomatic infection also called subclinical. Methods: A total of 179 patients undergoing replacement of CIED (cardiac implanted electronic devices) in Beijing hospital and Fuwai Hospital between January 2011 and October 2014 were recruited. Microbiological cultures of blood and generator pockets were consecutively obtained. Patients with clinical evidence of CIED infection were excluded. Patients were regularly followed up 60 months after discharge. Univariate and multivariable analyses were performed to identify significant risk factors for positive generator pockets culture patients. Five different inflammatory factors (CRP, IL-1, IL-6, MCP, PCT) were measured in 108 patients randomly selected from patients above, and the differences of inflammatory factors were analyzed between patients with positive pocket tissue cultures and patients with negative pocket tissue cultures. The inflammatory factors of 40 normal people were compared with the patients above too. Results: All blood cultures of the 179 patients were negative. Positive cultures from the generator pocket were found in 25 patients (14.0%). The most common bacteria isolated were coagulase negative staphylococci (76.0%). A multivariable logistic regression identified that male sex (P = 0.001, OR = 14.001, 95%CI: 2.825~69.401), antibiotic use 3 months before implantation (P = 0.002, OR = 27.935, 95%CI: 3.446~226.437), antiplatelet therapy (P = 0.008, OR = 3.761, 95%CI: 1.406~10.058) as independent risk factors for asymptomatic bacterial colonization of generator pockets. 4% patients with positive pocket culture showed clinical sign of infection during 60 months follow-up, while none of patients with negative pocket culture reported any sign of CIED relevant infections. Significant difference in inflammatory factors (including CRP, IL-1, IL-6, MCP, PCT) had been identified between patients who replaced CIED and the normal control group, however there was no relevance between inflammatory factors and generator pocket cultures even when all the fundamental clinical complications were excluded. Conclusion: 14.0% of patients undergoing CIED replacement have an asymptomatic bacterial colonization of generator pockets. Independent factors for positive pockets culture is male sex, antibiotic use 3 months before implantation, antiplatelet therapy 0.4% of patients with positive pocket culture develop clinical CIED infection. Inflammatory factors are significantly elevated in patients undergoing CIED replacement suggesting a strong inflammatory reaction in those patients, however, there is not sufficient evidence indicating predictive value of inflammatory factors in early diagnosis of subclinical CIED infections.

Continue Reading

Diagnostic value of different serum diagnostic models on liver fibrosis

Objective: To analyze the preoperative serological indexes of patients with segmental hepatectomy and establish serum diagnostic models, and to evaluate the application value of serum diagnostic model in liver fibrosis. Methods: Serological indexes of patients undergoing segmental hepatectomy in our hospital from June 2017 to December 2019 were collected retrospectively. Four hepatic fibrosis diagnostic models of aspartate aminotransferase/platelet ratio index (APRI), gamma glutamyl transpeptidase/platelet ratio index (GPR), fibrosis index based on four factors (FIB-4) and AST/ALT ratio (AAR) were calculated. ROC curve was used to evaluate the diagnostic ability of each diagnostic model for ≥S1, ≥S2, ≥S3 and ≥S4 liver fibrosis groups. Results: The three models of APRI, GPR and FIB-4 had statistical significance for the four groups of liver fibrosis with the range of P value (0.000~0.049); AAR was not significant for each group. FIB-4 had the best diagnostic performance in different stages of liver fibrosis, in which the diagnostic value of ≥S1 stage was the highest with the AUC 0.960. The critical value calculated by the maximum value of Jordan index was 0.850. Conclusion: Three serum diagnostic models of APRI, GPR and FIB-4 can indicate different stages of liver fibrosis, and FIB-4 model is the best for ≥S1 stage of liver fibrosis.

Continue Reading

Application of Digital Thoogenesis System in Pulmonary Bronchial pleural fistula treatment

Background and Objective: The digital drainage system (DDS) can play a positive role in promoting early and rapid recovery after minimally invasive pneumonectomy. This study was conducted to observe and summarize the clinical effect of the digital drainage system for bronchopleural fistula after pulmonary surgery. Methods: A total of 30 patients with bronchopleural fistula after pulmonary surgery admitted to our hospital from January 2012 to January 2021 were analyzed. Twelve patients were treated with digital thoracic drainage system (the digital group) and 12 patients with traditional thoracic drainage fluid bottle (the traditional group). There were no statistically significant differences between the two groups in gender, age, maximum diameter, benign and malignant lesions. The relevant clinical data were summarized and analyzed, and the duration of catheter drainage and hospital stay were compared between the two groups. Results: Compared with the traditional group, the digital group had higher cure rate, shorter catheter drainage time [34.00 ± 6.700 vs 57.83 ± 8.313, P = 0.049], and shorter hospital stay [33.25 ± 5.619 vs 49.06 ± 5.030, P = 0.048]. The cure rate and treatment period were significantly better than the traditional group and the current literature reports. Conclusion: Digital drainage device is a safe and effective method for the treatment of bronchopleural fistula after pulmonary surgery, and it should be considered in the treatment of bronchopleural fistula by shorting the number of days of drainage and hospital stay.

Continue Reading